Revolutionising Point-of-Care Diagnostics
Market Challenge in Point of Care Diagnostics
Current Virus Screening Tools are slow, invasive, unreliable, expensive, and lack multiplexing capabilities.
A non-invasive, rapid, accurate, and cost effective diagnostic at the point of care.
Solution
Examin’s Multiplex Breathalyser
Non-invasive: No swabs, no needles. Just a simple breath test.
Rapid Results: Accurate and advanced realtime detection in under 2 minutes.
Multiplex Detection: Identifies multiple viruses and diseases, including COVID-19 and influenza.
Cost Effective: Consumable breath guard for swift, cost effective testing.
Product Overview
Powered by a revolutionary Biosensor, using Aptamer Coating technology to detect viral particles in exhaled breath.
Detects actual viral presence, not just proteins or antigens.
Universal adaptability that can be rapidly and easily updated for new and emerging viruses.
Works at all infection stages, enabling earlier and more reliable realtime diagnosis.
Examin’s Diagnostic Process
Step 1. Load consumable tip.
Step 2. Patient blows.
Step 3. Instant test report.
Step 4. Eject consumable tip.
After the test, the results are given a unique ID number and sent to the operator’s tablet.
Evidence of Accuracy
Laboratory and Field Trials
Examin have conducted 100 controlled patient trials under rigorous protocols to assess viral detection efficacy.
Trials achieved 97% accuracy (compared to PCR’s 99.8%). Only 2 false negatives and 1 false positive recorded.
Human Factor Trials
Examin has conducted several hundred human factor field trials under rigorous protocols for viral detection efficacy. The trials were conducted in Australia and Malaysia over a 12-month period. Several changes have been made following each round of tests to improve reliability and accuracy.
With clear evidence of a working technology, the next stage is clinical processes. Clinical trials will follow to inform regulatory aspects.
Technology Overview
Signal Detection: The microprocessor continuously monitors the sensors’s output readings with a threshold based detection.
Machine learning and AI: The threshold is established via extensive testing, allowing the device to learn how to determine an accurate result that identifies the presence of the target virus or disease. A neural network will continually refine it’s detection algorithms, improving accuracy and sensitivity.
Market Analysis
Examin Breath Test: A breakthrough solution that is set to lead the virus and disease screening market.
Analysis is relative to key PoC features sought by end-customers, such as in air travel, sporting events, hospitality, healthcare, etc.
Examin’s breath test will be real time, delivering a result in under 2 minutes. Examin’s breath test will be lower cost than PCR and lab antigen tests. No reagants are needed. Examin’s breath test will detect the virus days earlier than other tests. Examin’s breath test will be non-invasive, only requiring the patient to blow. Examin’s breath test can detect multiple strains and viruses at once unlike home antigen tests. Examin’s breath test matches the accuracy rate of PCR tests. Examin’s test device is portable and small.
Market Opportunity
Key Growth Drivers
Real-time, Point of Care testing: Rising demand for rapid, on-site diagnostics is transforming the healthcare industry.
Increased Funding: Substantial government and private investments are accelerating rapid diagnostic innovations.
Medium-term Developments
New sensor technologies, GFET, VOC sensors, and multiplexing will enable the expansion of our product offering into new areas of diagnostics at POC. Cancer, TB and many other diseases are being developed.
Adressible Market from 2024 to 2030
Key Growth Drivers
C19 Diagnostics: US$22.40B 2024 US$49.97B 2030 50.23% increase.
Influenza: US$1.63B 2024 US$2.41 2030 47.85% increase.
RSV: US$1.46B 2024 US$4.59B 2030 212.4% increase.
TB: US$2.19B 2024 US$3.29 2030 50.23% increase.
GFETs, or Graphene Field-Effect Transistors, are a type of transistor that utilises graphene, a single layer of carbon atoms, as its channel. Here’s a breakdown of what they are:
How they work:
When a voltage is applied to the gate, it creates an electric field that alters the conductivity of the graphene channel. This modulation of conductivity allows for precise control of the current flow between the source and drain.
Graphene’s sensitivity means that even subtle changes in its environment (e.g., the presence of specific molecules) can significantly affect its conductivity.
Key Characteristics and Advantages:
High Sensitivity – Graphene’s atomic thinness makes it extremely sensitive to changes in its surroundings, enabling the detection of minute quantities of substances.
Fast Response Times – Graphene’s high electron mobility allows for rapid changes in conductivity, resulting in fast response times.
Versatility – GFETs can be adapted for a wide range of applications, including biosensing, chemical sensing, and electronic devices.
AeroFlu Sentinel
Early Bird Alert: Revolutionise Avian Influenza Detection!
Protect your poultry, safeguard public health, and stay ahead of avian influenza outbreaks with this groundbreaking device that provides real-time, airborne detection of the H5N1 virus, allowing for rapid response and containment.
Key Features:
- Ultra-sensitive biosensor Technology Detects minute traces of avian influenza virus particles in the air, providing early warning signals.
- Continuous Monitoring: 24/7 surveillance ensures constant protection, minimising the risk of undetected outbreaks.
- Rapid Results: Get instant alerts and data analysis via our user-friendly mobile app and web portal.
- Automated Sampling: No manual handling is required; the AeroFlu Sentinel autonomously collects and analyses air samples.
- Location-Specific Data: Pinpoint outbreak locations with precise GPS tracking and environmental data integration.
- Robust and Weatherproof: Designed for outdoor and indoor use, enduring harsh environmental conditions.
- Easy Integration: Seamlessly connect with existing farm management systems for streamlined data sharing.
Benefits:
- Prevent Economic Losses: Protect your poultry stock and avoid costly culls.
- Enhance Biosecurity: Implement proactive measures to control the spread of avian influenza.
- Safeguard Human Health: Minimize the risk of zoonotic transmission.
- Improve Response Time: React swiftly to outbreaks and implement targeted containment strategies.
- Peace of Mind: Gain confidence in your biosecurity measures with reliable, real-time detection.
